Studies

We oppose pseudoscience. For over 8 years, we have led and collaborated with with top research institutions to make meaningful discoveries in endurance performance and Oleuopien (OLE), subjecting them to the scrutiny of the scientific community through publication in high-impact, peer-reviewed journals. Our commitment to rigorous research sets us apart from other endurance supplements.

Clinical studies

Studies in humans to assess safety, efficacy, and optimal dosages of new treatments or interventions, often conducted in multiple phases.

DATE TITLE PUBLICATION
ONGOING
Effects of an oleuropein-based drink on performance and fatigue in elite athletes: a real-life placebo-controlled RCT on perceived and measured efficacy during a high intensity cycling training camp
A clinical study with elite cyclists found that a supplement containing oleuropein, B-vitamins, and magnesium significantly improved performance and reduced fatigue. The supplement led to a 25% increase in maximal power output and a 16% boost in perceived performance. Furthermore, athletes who took the supplement experienced 38% less fatigue during high-intensity training.
NOT YET PUBLISHED
FEB 2024
Effects of olive leaf extract on exercise performance and muscle mitochondrial response in young healthy adults
This study demonstrates that supplementing with olive leaf extract (OLE) can enhance the body's response to moderate-intensity continuous exercise. It achieves this by improving skeletal muscle function, specifically by activating pyruvate dehydrogenase (PDH) and influencing genes related to mitochondrial and inflammatory responses.
FEB 2022
Effect of Supplementation with Olive Leaf Extract Enriched with Oleuropein on the Metabolome and Redox Status of Athletes' Blood and Urine-A Metabolomic Approach
This study investigated how an oleuropein-enriched olive leaf extract supplement affects the metabolism of healthy young male athletes. Researchers found that taking the supplement for one week influenced specific metabolic pathways, particularly those related to tryptophan and acylcarnitines. The results suggest that the supplement may enhance serotonin turnover and improve performance, in addition to potentially altering the body’s lipid profile and antioxidant status.

Pre-clinical studies

Lab experiments conducted to evaluate safety, efficacy, and mechanisms of new treatments before human trials.

DATE TITLE PUBLICATION
FEB 2025
Mitochondrial calcium uptake declines during aging and is directly activated by oleuropein to boost energy metabolism and skeletal muscle performance - PubMed
This study discovered that oleuropein, a natural compound from olives, can activate mitochondrial calcium uptake, a process that is often impaired during aging. By doing so, it improves energy metabolism in muscle cells. This leads to enhanced endurance and muscle performance in both young and aged mice